Patient characteristics, symptoms, and urodynamic parameters associated with detrusor contraction duration in women

Background There is a lack of understanding the clinical significance detrusor contraction duration (DCD) measured on urodynamic studies (UDS). We aimed to identify patient characteristics, presenting symptoms and parameters associated with DCD in women. Methods Using single-institution database UDS (2015-2019), 405 female patients measurable contractions were identified. Baseline analyzed. Bladder outlet obstruction (BOO) was characterized using Blaivas-Groutz nomogram. Wilcox Rank Sum Tests used for descriptive statistics, univariable generalized linear model conforming gamma distribution used. Results Median age 65 years (IQR 52-75), BMI 27.5 kg/m2 23.9-31.1) 90 seconds 57-124). On analysis, degenerative disc disease (β = -17.9, p 0.02), pelvic radiation -31.91, 0.04), stress incontinence -14.11, 0.03) reduced DCD. Black race longer 22.92, 0.01). Analysis revealed significant increase per unit bladder capacity 0.08, p<0.001), pressure (Pdet) at maximum flow (Qmax) 0.96, Pdet 1.2, p<0.001). In contrast, decrease noted Qmax -1.43, Finally, mild 34.4, moderate 72.52, severe 64.6, p<0.001) BOO all increased Conclusions women seconds. Longer greater degree BOO, higher Pdet, Qmax, capacity. Disc disease, irradiation are Further needed evaluate predictive value